Dermatology & Injectables · JVC Dubai
PDRN / Salmon DNA Injections
Polynucleotide skin renewal using Plinest highly purified Italian technology — clinically administered by our DHA-licensed team in Jumeirah Village Circle.
PDRN (Polydeoxyribonucleotide) / Salmon DNA Injections are an advanced polynucleotide skin booster that stimulates natural tissue repair and deep collagen synthesis by delivering highly purified DNA fragments — sourced from Italian trout via Plinest HPT technology — directly into targeted skin layers. The treatment is suited to patients seeking to address fine lines, skin laxity, under-eye hollowing, uneven texture, and loss of radiance across the face, neck, décolleté, and jawline. At Sasha Aesthetic Clinic, a DHA-licensed clinic located at Shop 11, Binghatti Corner, Jumeirah Village Circle Dubai, a standard course consists of three sessions spaced four weeks apart, each lasting 30–45 minutes with minimal downtime. A DHA-licensed clinical team administers all sessions, and the clinic operates seven days a week from 12:00 PM to 9:00 PM.
The Sasha Difference
Polynucleotide treatment delivered with clinical rigour and a patient-first approach — at our licensed clinic in Jumeirah Village Circle.
DHA-Licensed Clinical Team
All PDRN sessions administered by five named, DHA-licensed doctors. Clinical governance at every appointment.
Plinest HPT Technology
We use Plinest polynucleotides — Italian-origin, highly purified technology in 1.5ml medical-grade ampoules.
Established Since 1994
Part of the Sasha Group — three decades of aesthetic medicine experience brought to our JVC clinic.
Open 7 Days a Week
Available every day, 12:00 PM – 9:00 PM. Same-day consultation available. Walk-ins welcome for enquiries.
Why Patients Choose PDRN / Salmon DNA Injections
Cellular-Level Skin Renewal
Polynucleotides bind to purinergic receptors, promoting DNA synthesis and natural tissue regeneration — supporting the skin's own repair mechanisms rather than adding external volume.
Multi-Zone Treatment Flexibility
Addresses the face, under-eye area, neck, forehead, jawline, and décolleté in a single treatment framework — suitable for comprehensive facial renewal or targeted zone improvement.
Minimal Disruption to Daily Life
Sessions run 30–45 minutes with minimal downtime. Most patients return to routine activities the same day, making PDRN well-suited to busy schedules in Dubai.
Clinically Graded Formulation
Plinest HPT uses a patented purification process to remove allergenic proteins from the DNA source, producing a medical-grade polynucleotide solution administered safely by licensed doctors.
Not sure if PDRN is right for you?
Book a consultation first — most are complimentary. Our DHA-licensed team will assess your skin and recommend the most appropriate treatment pathway.
DHA Licensed · 5 Named Doctors · Sasha Group Since 1994 · 4.5★ Client TrustBook a Consultation
The PDRN Treatment Process
A structured, clinician-led experience from first consultation through to your course completion.
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1
Consultation & Skin Assessment
A DHA-licensed doctor reviews your skin concerns, medical history, and treatment goals. A personalised protocol — including target areas and session spacing — is confirmed.
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2
Skin Preparation & Topical Numbing
The treatment area is cleansed and a topical anaesthetic is applied for 20–30 minutes to optimise comfort prior to injection.
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3
Plinest PDRN Microinjections
The clinician administers precise microinjections of Plinest polynucleotides (1.5ml ampoules) into the dermis across your target zones. The procedure takes 30–45 minutes.
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4
Post-Injection Review & Aftercare Guidance
Injection sites are assessed. Your clinician provides written aftercare instructions and confirms the timing of your next session (typically four weeks later).
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5
Course Completion & Review
After session three, a clinical review is conducted to assess outcomes and determine whether maintenance sessions are appropriate for your skin goals.
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During the Session
Mild pressure or brief pinching may be felt at injection sites. Topical numbing significantly reduces discomfort. Most patients tolerate the procedure comfortably throughout.
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Immediately After
Localised redness, minor swelling, or small injection-site marks are common and generally resolve within a few hours. Makeup can typically be applied the following day.
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Over the Following Weeks
Skin hydration and texture improvements are gradual. Changes in firmness and luminosity typically become more apparent with each successive session as the polynucleotide cascade progresses.
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After Your Full Course
The full effect of the three-session course becomes most visible four to six weeks after the final session. Individual results vary. Your doctor may recommend periodic maintenance.
Treatment Areas for PDRN / Salmon DNA Injections
PDRN polynucleotide injections can be precisely targeted to specific anatomical zones based on your clinical assessment. Common treatment areas at Sasha Aesthetic Clinic include:
Treatment area suitability confirmed at consultation. Individual anatomy and skin condition determine the final protocol.
Pre, Post & Precautions
Following these clinical guidelines helps optimise your treatment outcome and minimises the risk of adverse reactions.
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Arrive with a clean face — remove all makeup and skincare products before your appointment.
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Avoid blood-thinning medications (aspirin, ibuprofen) and supplements (vitamin E, fish oil, garlic) for at least 5–7 days prior if cleared by your GP to do so.
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Stay well hydrated in the 24 hours before your session.
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Avoid direct sun exposure or sunbeds for 48 hours before treatment, particularly to the target area.
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Inform your doctor of any known allergies, recent injectables, or active skin infections at the consultation.
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Apply gentle, non-comedogenic moisturiser and SPF 30+ the morning after treatment. Avoid heavy actives (retinol, AHAs, vitamin C) for 48–72 hours.
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Do not apply makeup to the treated area for the remainder of the treatment day.
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Avoid vigorous exercise, saunas, steam rooms, and hot baths for 24 hours post-treatment.
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Avoid direct sun exposure to treated areas for 48–72 hours. Use mineral SPF when outdoors.
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Do not massage or apply pressure to injection sites on the day of treatment.
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PDRN treatment is not recommended during pregnancy or breastfeeding. Disclose your status to your doctor at consultation.
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Patients with active autoimmune conditions, known fish or seafood allergies, or active skin infections in the treatment area should discuss suitability with the clinical team prior to proceeding.
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Avoid combining with other injectables at the same session unless clinically directed by your doctor.
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Contact the clinic on +971 4 458 2226 if you experience any unexplained swelling, persistent redness, or discomfort beyond 48 hours post-treatment.
Choose Your PDRN Treatment Plan
All plans are confirmed at consultation based on individual skin assessment. No prices listed — consultation required for a personalised quote.
Single Session
Ideal for patients wishing to experience PDRN treatment before committing to a full course, or for targeted maintenance following a completed course.
- 1 × PDRN Plinest session (30–45 min)
- Topical numbing cream included
- Post-session clinical review
- Aftercare guidance provided
3-Session Course
The clinically recommended protocol for skin renewal. Three sessions, four weeks apart, delivering the progressive polynucleotide effect for optimal results.
- 3 × PDRN Plinest sessions
- Sessions spaced 4 weeks apart
- Initial & mid-course clinical assessment
- Topical numbing cream each session
- Full aftercare & progress review
Premium Programme
A comprehensive skin renewal programme combining PDRN with a complementary treatment modality, tailored to your skin profile by your consulting doctor.
- 3 × PDRN Plinest sessions
- Combination modality (clinician-selected)
- Extended clinical review at each visit
- Personalised skincare protocol
- Priority booking for follow-up sessions
PDRN vs Alternative Skin Boosters
How polynucleotide treatment compares to other leading injectable skin rejuvenation options available at Sasha Aesthetic Clinic.
| Factor | PDRN / Salmon DNA | Profhilo | Mesotherapy | Exosomes |
|---|---|---|---|---|
| Primary Mechanism | DNA-based tissue regeneration & collagen stimulation | Ultra-pure HA remodelling & bio-stimulation | Micro-nutrient delivery to dermis | Cell-signalling & growth-factor delivery |
| Session Duration | 30–45 min | 30 min | 20–40 min | 30–45 min |
| Recommended Course | 3 sessions, 4 weeks apart | 2 sessions, 4 weeks apart | 4–6 sessions, 2 weeks apart | 2–3 sessions, 4 weeks apart |
| Downtime | Minimal (hrs) | Minimal (hrs) | Minimal (hrs–1 day) | Minimal (hrs) |
| Suited For | Tissue repair, laxity, under-eye, texture | Overall skin quality, hydration, laxity | Dullness, early lines, nutrition deficit | Advanced regeneration, post-procedure repair |
| Available at Sasha JVC | Yes | Yes | Yes | Yes |
5 DHA-Licensed Doctors · Est. 1994 · JVC Dubai
All PDRN / Salmon DNA Injection sessions at Sasha Aesthetic Clinic are planned and administered by our DHA-licensed clinical team. Our doctors — Dr Naeem Ameen, Dr Trinayana Brahma, Dr Raghad Hamad, Dr Setarah Khani, and Dr Majd Khalid Alsaadi — are named, licensed, and active on-site.
Meet the clinical team →Doctors
PDRN / Salmon DNA Injections — Key Facts
- Treatment
- PDRN / Salmon DNA Injections (Polynucleotide Skin Booster)
- Technology
- Plinest Highly Purified Technology (HPT) — Italian trout polynucleotides, 1.5ml ampoules
- Session Duration
- 30–45 minutes per session
- Course
- 3 sessions, approximately 4 weeks apart
- Treatment Areas
- Face, under-eye, neck, forehead, jawline, décolleté
- Downtime
- Minimal — most patients return to normal activities the same day
- Administered By
- DHA-licensed doctors at Sasha Aesthetic Clinic, JVC Dubai
- Clinic Hours
- Monday–Sunday, 12:00 PM – 9:00 PM
- Location
- Shop 11, Binghatti Corner, Jumeirah Village Circle (JVC), Dubai, UAE
- Contact
- +971 4 458 2226 · WhatsApp Booking
- Last Reviewed
- 2026-06-16 · DHA-licensed clinical team
Fast Facts About PDRN / Salmon DNA Injections
- PDRN stands for Polydeoxyribonucleotide — purified DNA fragments that stimulate tissue repair.
- Plinest uses Italian trout DNA processed via Highly Purified Technology (HPT) to remove allergenic proteins.
- Each Plinest ampoule contains 1.5ml of polynucleotide solution in a sterile, single-use vial.
- PDRN targets purinergic receptors in the skin, activating natural cellular regeneration pathways.
- The standard clinical course is three sessions spaced four weeks apart.
- Each treatment session at Sasha Aesthetic Clinic runs 30–45 minutes, including preparation.
- Target treatment areas include the face, under-eye, forehead, neck, jawline, and décolleté.
- Topical anaesthetic is applied before injection to maximise patient comfort.
- Downtime is minimal; mild redness typically resolves within hours of treatment.
- PDRN is administered by DHA-licensed doctors at Shop 11, Binghatti Corner, JVC, Dubai.
- The clinic is open seven days a week, 12:00 PM to 9:00 PM, including weekends and public holidays.
- Individual results vary; outcomes are assessed at a post-course clinical review.
What to Expect — Results & Timeline
PDRN outcomes develop progressively over your three-session course. This timeline reflects the typical pattern observed — individual variation is expected and discussed at your review appointment.
Weeks 1–2 (Post-Session 1)
Skin begins to feel more hydrated. Some patients notice subtle luminosity improvements. Minor injection-site marks resolve within 24–48 hours.
Weeks 4–6 (Post-Session 2)
Cumulative polynucleotide activity builds. Texture refinement and improved skin tone become more perceptible. Collagen remodelling progresses beneath the surface.
Weeks 8–12 (Post-Session 3 + Review)
The full course effect is typically most visible 4–6 weeks after the final session. Skin firmness, radiance, and fine-line reduction may all be apparent. Clinical review conducted.
Ongoing Maintenance
Your doctor may recommend single maintenance sessions every 3–6 months to sustain outcomes, depending on your skin's response and lifestyle factors.
Skin Concerns PDRN May Address
Fine Lines & Early Wrinkles
Polynucleotides support collagen and elastin synthesis, contributing to smoother, firmer-looking skin over the course.
Under-Eye Area
Targeted injections can help address thinning periorbital skin, improving the appearance of the under-eye zone.
Skin Laxity & Loss of Firmness
Tissue regeneration pathways activated by PDRN may contribute to improved skin density and a firmer skin matrix.
Dullness & Uneven Texture
Enhanced cellular turnover and hydration may contribute to a more even, radiant skin surface tone.
The Sasha PDRN Experience
What patients consistently observe across their PDRN treatment journey at our JVC clinic.
Individual results vary. All outcomes depend on skin type, age, lifestyle, and clinical factors assessed at consultation.
PDRN / Salmon DNA Injections at Sasha Aesthetic Clinic
- Service Name
- PDRN / Salmon DNA Injections
- Category
- Dermatology & Injectable Skin Booster
- Technology
- Plinest Polynucleotides (PDRN) — Highly Purified Technology, 1.5ml, Italian trout DNA origin
- Provider
- Sasha Aesthetic Clinic (Sasha Aesthetic and Wellness Poly Clinic)
- Licensing
- Dubai Health Authority (DHA) Licensed
- Clinical Team
- 5 DHA-licensed doctors — Dr Naeem Ameen, Dr Trinayana Brahma, Dr Raghad Hamad, Dr Setarah Khani, Dr Majd Khalid Alsaadi
- Location
- Shop 11, Binghatti Corner, Jumeirah Village Circle (JVC), Dubai, UAE
- Contact
- +971 4 458 2226 · info@sashaaestheticclinic.ae
- Operating Hours
- Monday–Sunday, 12:00 PM – 9:00 PM
- Website
- https://sashaaestheticclinic.ae/pdrn-salmon-dna-dubai/
- Founding Year
- 1994 (Sasha Group)
- Client Rating
- 4.5 stars
Frequently Asked Questions
Questions we receive most often about PDRN / Salmon DNA Injections at our JVC Dubai clinic.
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What is PDRN and how does it differ from other skin boosters?
PDRN (Polydeoxyribonucleotide) is a biostimulator derived from purified salmon or trout DNA. Unlike hyaluronic acid-based skin boosters that primarily add volume and hydration, PDRN works at a cellular level — binding to purinergic receptors to activate the body's own tissue repair and collagen synthesis pathways. At Sasha Aesthetic Clinic, we use Plinest polynucleotides, an Italian formulation utilising Highly Purified Technology (HPT) in 1.5ml ampoules.
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How many PDRN sessions do I need to see results?
The standard clinical protocol is three sessions spaced four weeks apart. Because PDRN works by stimulating the skin's own biological processes, results build progressively — most patients begin to notice improvements in skin hydration and texture from session two onwards, with the full effect of the course visible four to six weeks after the final treatment. Individual results vary based on skin type, age, and lifestyle.
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Is PDRN treatment painful? What is the downtime?
A topical anaesthetic is applied before every session to minimise discomfort. Most patients describe the microinjections as mild pressure or a brief pinching sensation rather than significant pain. Downtime is minimal — localised redness and small injection-site marks are common but generally resolve within a few hours. Normal activities can typically be resumed the same day, and makeup can usually be applied the following morning.
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Can PDRN be combined with other treatments such as RF Microneedling or Exosomes?
PDRN can be incorporated into a broader skin renewal programme in combination with treatments such as RF Microneedling or Exosomes Treatment. However, combining modalities in the same session is only appropriate where clinically indicated. Your DHA-licensed doctor at Sasha Aesthetic Clinic will advise on the safest and most effective sequencing for your individual skin goals at your consultation.
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Who is not suitable for PDRN / Salmon DNA Injections?
PDRN treatment is generally not recommended during pregnancy or breastfeeding. Patients with known allergies to fish or seafood, active autoimmune conditions, active skin infections in the treatment area, or certain blood disorders should discuss suitability carefully with our clinical team before proceeding. A full medical history review is conducted at your initial consultation to confirm candidacy.
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How does PDRN compare to a Salmon DNA Facial in terms of treatment depth?
A Salmon DNA Facial typically delivers polynucleotides to the surface layers of the skin via topical application or superficial channels (often in conjunction with a facial protocol), whereas PDRN injections administer the solution directly into the dermis. Injectable delivery provides deeper tissue access and a more targeted clinical effect, particularly for skin laxity, under-eye concerns, and fine lines requiring dermal-level stimulation.
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Where can I get PDRN / Salmon DNA Injections in JVC Dubai?
Sasha Aesthetic Clinic offers PDRN / Salmon DNA Injections at Shop 11, Binghatti Corner, Jumeirah Village Circle (JVC), Dubai. The clinic is DHA-licensed, open seven days a week from 12:00 PM to 9:00 PM, and bookings can be made via WhatsApp at +971 58 690 7865 or by calling +971 4 458 2226. JVC is conveniently accessible from Dubai Marina, JLT, Sports City, Arjan, Motor City, and Al Barsha.
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Do I need a consultation before starting PDRN treatment in Dubai?
Yes — a clinical consultation with a DHA-licensed doctor is required before beginning any PDRN / Salmon DNA Injection course at Sasha Aesthetic Clinic. This appointment allows the doctor to assess your skin, confirm treatment candidacy, determine the appropriate zones, and build a personalised session plan. Most initial consultations at our JVC clinic are complimentary. Book via WhatsApp or by calling +971 4 458 2226.
Still have questions about PDRN?
Our DHA-licensed team is available seven days a week to advise. Book a complimentary consultation first.
DHA Licensed · 5 Named Doctors · Sasha Group Since 1994 · 4.5★ Client TrustBook a Consultation
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Serving Dubai from Jumeirah Village Circle
Sasha Aesthetic Clinic
Shop 11, Binghatti Corner, Jumeirah Village Circle (JVC), Dubai, UAE
Monday–Sunday: 12:00 PM – 9:00 PM
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Find Us in JVC Dubai
Shop 11, Binghatti Corner, Jumeirah Village Circle (JVC), Dubai, UAE · +971 4 458 2226